Brayan and Andres will see their lives give a U-turn when a nurse who is on the verge of death confesses to Antonia, a lady from high society, that when she attended her on the delivery of her son, she made a slight mistake: she changed her baby. Thirty years later, Antonia will teach them a lesson. She will make them exchange their lives with the only aim of showing them that they have missed the chance of enjoying what life has granted them. Brayan will go from being poor to being wealthy, which would be the dearest dream of any man, especially of a lazy man like him. He will have to strive to manage a company and not to disappoint his biological mother. However, rather than enjoying his new environment, he will find it more and more demanding. The pressure and stress of meeting the expectations of everybody around will make him become an unsociable, bad-tempered, depressed person. To cap it all, his friends will no longer recognize him and will not want to be around him. He will feel he can not trust anybody and start behaving like paranoid. On the other hand, despite leading an affluent lifestyle and despite the power he gained, Andres has become a cold man, who has not been capable of enjoying the peace of mind money can bring. Now a poor man, Andres will have to learn that it is not enough to be intelligent, but it is also necessary to get on well with people. Brayan has been dating Rosmery, a good-natured girl who will turn out to be the peak of the iceberg for these two men. Andres is engaged to the beautiful Fernanda, the most highly valued and coveted model in the country, but she only wants to remain with him because of his fortune. In the end, Andres will fall in love with Rosmery and Brayan will marry Fernanda, only to find out later that she is a villain. What is easier? To go from being poor to being rich or the other way around? (Nuevo rico, nuevo pobre).