The Soul Sisters are two heroines who give everything for their family, their artistic career and a musical genre which showers them with fame and glory, but takes away part of their childhood and youth. Nelly and Fabiola Calle hold on to their voices and they set out to position the popular music, a genre that was despised by radio stations and record labels. Their life will not be easy since they will be forced to be the bread feeders of the family. As young children they will suffer because of their father and as adults because of their husbands. They will live stories of abandonment and lack of love as dramatic as the lyrics of their songs. Their biggest achievement is that they started from the bottom and with everything against them, they hang on to their love for music and the overwhelming power of their two voices to achieve the impossible: to position and sell to society a musical genre that only few artists were able to reach recognition with.